Arterioscler Thromb Vasc Biol. 2003 Feb 1;23(2):151-2.

Omega-3 fatty acids and cardiovascular disease: new recommendations from the American Heart Association.

Kris-Etherton PM, Harris WS, Appel LJ; AHA Nutrition Committee. American Heart Association.

“For patients with documented CHD, the AHA recommends 1 g of EPA and DHA (combined) per day. This may be obtained from the consumption of oily fish or from omega-3 fatty acid capsules, although the decision to use the latter should be made in consultation with a physician. The amount of EPA and DHA in fish and fish oil is presented in the recent AHA Scientific Advisory on omega-3 fatty acids and CVD”.

“An EPA+DHA supplement may be useful in patients with hypertriglyceridemia. Two to four grams of EPA+DHA per day can lower triglyceride 20% to 40%. Patients taking more than three grams of these fatty acids from supplements should do so only under a physician’s care. Very high ("Eskimo") intakes could cause excessive bleeding in some people.”

PMID: 12588750